Drug addictions: new insight into causes, comorbidity and potential treatments

Mitophagy: New Insight into the Cardiovascular Aging  

New Insight into the Relation between Adiponectin and Diabetes

Diabetes mellitus is a group of metabolic diseases. Insulin resistance is defined as a state that needs more insulin to get the biological effects achieved by a lower amount of insulin in the normal state. Several molecules which are secreted through adipocytes have been involved in insulin resistance and type 2 diabetes mellitus. Adiponectin as a 244 amino acid protein is exclusively expressed...

Drug-induced hypoglycaemia--new insight into an old problem.

OBJECTIVE To review the causes of drug-induced hypoglycaemia in patients not taking hypoglycaemic medications. DESIGN Retrospective study. SETTING Regional hospitals in Hong Kong. PATIENTS Patients with suspected drug-induced hypoglycaemia without a known history of exposure to hypoglycaemic agents, referred to the Hospital Authority Toxicology Reference Laboratory from June 2005 to March...

New Insight into the Molecular Drug Target of Diabetic Nephropathy

Diabetic nephropathy (DN) lowered quality of life and shortened life expectancy amongst those affected. Evidence indicates interaction between advanced glycation end products (AGEs), activated protein kinase C (PKC) and angiotensin II exacerbate the progression of DN. Inhibitors of angiotensin-converting enzyme (ACEIs), renin angiotensin aldosterone system (RAAS), AGEs, and PKC have been tested...

New insight into superconductivity

NOVEMBER 2008 | VOLUME 11 | NUMBER 11 13 The physics of high-temperature cuprate superconductors in the overdoped regime, where superconductivity is suppressed, is something of a mystery. But first-principle calculations by researchers in the US and Switzerland appear to confirm a recent suggestion that ferromagnetism can destroy superconductivity at high doping levels [B. Barbiellini and T. Ja...